We are changing the status quo to make the impossible possible, by expanding the scope of new targets for drug development through targeted protein manipulation.

Technology

Our science and technology are rooted in our deep and extensive knowledge of neuroscience and proteome informatics. By combining these with our computational strategies, we have developed three innovative platforms that enable us to us to design therapeutic interventions by manipulating proteins in ways that are not amenable using small molecules, antibodies, antisense oligos, or more classical protein degradation technologies known as PROTAC.

Through our novel discovery programs, we are able to identify key domains of disease related proteins, and design lead compounds that offer new therapeutic approaches by:

 

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